Effect of Goji Berry Consumption on Biochemical Parameters

Eastern Mediterranean University

Status: Completed

Conditions: Healthy; Hyperlipidemias

Treatments: Dietary Supplement: Goji Berry

Study type: Interventional

Funder types: Other

Identifiers

NCT06190587

2022-22/01

Details and patient eligibility

About

Goji Berry as a functional food have been shown to reduce risk of hyperlipidemia, type 2 diabetes, etc. However, human studies are limited in this area. In this study, it has been aimed to evaluate the effect of goji berry consumption on some biochemical parameters in healthy individuals.

Full description

Healthy individuals have been divided into control and study groups. Individuals in both group have same characteristics such as age, gender, and body mass index (Control Group: 35 individuals - Study Group: 35 individuals). Both group were asked to maintain their normal diets. In addition, the study group consume 20 g of dried goji berry per day and did not consume any fruit with a similar antioxidant content during the 8 weeks study period. The control group was asked to exclude goji berry and similar fruits with high antioxidant content from their diet during the 8 weeks study period. The 20 g goji berry for per day was given weekly to each individual in a study group in transparent bags. At the beginning of the study and every 15 days, food consumption record for 3 consecutive days (2 weekdays and 1 weekend), a 3-day physical activity record, and anthropometric measurements (weight, height, waist and hip circumferences, body composition analysis) were taken. Blood parameters (total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), triglyceride, glucose, insulin, homeostatic model assessment of insulin resistance (HOMA-IR), HbA1c) of individuals were taken at the beginning and the end of the study.

Enrollment: 70 patients

Sex: All

Ages: 19 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI between 20-25 kg/m²
• Female individuals are not in the period of lactation and menopause,
• Absence of any chronic or acute disease diagnosed by a physician,
• No allergies to Goji Berry
• Not consuming goji berry and similar fruits regularly for the last 1 month.
• Not being in the process of body weight loss
• Not doing strenuous physical activity
• Not taking any medication or antioxidant vitamin support
• Not smoking
• Not consuming alcohol (moderate alcohol consumption)

Exclusion criteria

Not meeting the criteria for inclusion in the study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

Control Group

No Intervention group

Description:

In control group participants had 8-weeks follow-up without any intervention.

Interventional Group

Experimental group

Description:

In interventional group participants had 8-weeks follow-up with 20 g/day goji berry consumption intervention.

Treatment:

Dietary Supplement: Goji Berry