Effect of Green Tea Extract on Lipids in Patients With Type 2 Diabetes (HDL)

Centro Universitario de Ciencias de la Salud, Mexico

Status: Completed

Conditions: Dyslipidemias; Diabetes Mellitus, Type 2; Arterial Stiffness

Treatments: Dietary Supplement: Green tea extract; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT04532385

CUCS-INTEC-MV-TEVE-002

Details and patient eligibility

About

The main objectives of this study were to evaluate the effect of a 12-week supplementation with GTE (400 mg every 12 hours) on serum lipids, arterial stiffness and inflammatory cytokines in patients with T2DM.

Full description

A 12 week randomized double-blind, placebo-controlled trial was conducted in patients with T2DM to evaluate the effect of green tea extract (sunphenon 90D, TAIYO international, Minneapolis, US) at a 400 mg/12 hrs dose or calcined magnesia (400 mg/12 hrs) on lipids, anthropometric variables, arterial stiffness and inflammatory cytokines.

Enrollment: 20 patients

Sex: All

Ages: 40 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with type 2 diabetes

Exclusion criteria

• Type 1 diabetes
• Smoking patients
• Ischemic heart disease
• Use of anti-inflammatory or antioxidant drugs
• Previously diagnosed liver or thyroid disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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20 participants in 2 patient groups, including a placebo group

GTE

Experimental group

Description:

Green tea extract, 400 mg every 12 hours for 12 weeks

Treatment:

Dietary Supplement: Green tea extract

Placebo

Placebo Comparator group

Description:

Calcined magnesia, 400 mg every 12 hours for 12 weeks

Treatment:

Dietary Supplement: Placebo