Effect of Growth Hormone (GH) on Cardiac Echos in GH Deficient Patients After Acromegaly Treatment

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Mass General Brigham

Status

Completed

Conditions

Acromegaly

Study type

Observational

Funder types

Other

Identifiers

NCT01302652
2010P002188

Details and patient eligibility

About

The purpose of this research study is to study the effects of growth hormone (GH) replacement on the heart. The investigators will study these effects in people who have been cured of acromegaly and then have developed growth hormone deficiency (GHD, not enough growth hormone).

Enrollment

20 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

age 18-75 history of acromegaly with biochemical cure growth hormone deficiency

Exclusion criteria

untreated thyroid disease within the past 3 months untreated adrenal insufficiency within the past 3 months uncontrolled hypertension congestive heart failure gonadal steroid therapy within the past 3 months pregnancy or nursing

Trial design

20 participants in 2 patient groups

GH deficient after acromegaly cure (on GH replacement)
Description:
Men and women with growth hormone deficiency following cure of acromegaly who are receiving growth hormone treatment.
GH deficient after acromegaly cure (not on GH replacement)
Description:
Men and women with growth hormone deficiency following cure of acromegaly who are not receiving growth hormone treatment.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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