Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy

Naval Military Medical University

Status and phase: Completed; Phase 4

Conditions: Bowel Preparation Scale; Adenoma Detection Rate

Treatments: Drug: polyethylene glycol; Dietary Supplement: gum+PEG

Study type: Interventional

Funder types: Other

Identifiers

NCT02507037

Gum-1

Details and patient eligibility

About

In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 150) used 2 L PEG before colonoscopy. Patients in group B (n = 150) were additionally advised to chew sugarless gum plus 2 L PEG, The overall quality of colonoscopy cleaning was evaluated using the Boston Bowel Preparation Scale by endoscopists who was blinded to the intervention. Difficulty of procedure, patients' tolerance, and adverse events were also evaluated.

Enrollment: 300 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All adults (18-65) who were referred for outpatient colonoscopy.

Exclusion criteria

• under 18 years or More than 65 years
• previous abdominal surgery
• major psychiatric disorders
• pregnancy
• presence of any contraindications for colonoscopy(eg, severe heart failure)
• recent inadequate colonoscopy history

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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300 participants in 2 patient groups, including a placebo group

gum+PEG

Experimental group

Description:

used 2L PEG+sugarless gum

Treatment:

Dietary Supplement: gum+PEG

PEG

Placebo Comparator group

Description:

only used 2L PEG

Treatment:

Drug: polyethylene glycol