Effect of Helicobacter Pylori Treatment on Idiopathic Central Serous Chorioretinopathy (ICSCR)

Tabriz University

Status and phase: Completed; Phase 2; Phase 1

Conditions: Central Serous Chorioretinopathy

Treatments: Drug: omeprazole, Amoxicillin, metronidazole

Study type: Interventional

Funder types: Other

Identifiers

NCT00817245

86-47

Details and patient eligibility

About

Etiology of ICSCR is not known however recent studies regard the role of immunologic and infectious processes in the pathogenesis of ICSCR.one of these hypothesis is the role of helicobacter pylori in the pathogenesis of ICSCR so perhaps treatment of h pylori have positive effect on the remission of ICSCR.

Full description

we will choose 50 cases of patients with ICSCR who are infected with h.pylori.25 cases will receive anti h.pylori regiment and 25 cases as controls will receive no medication.then we will compare the time of submacular fluid resorption and macular thickness and visual acuity among these two groups.

Enrollment: 50 patients

Sex: All

Ages: 28 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• the persons who are infected with helicobacter pylori and have ICSCR

Exclusion criteria

• history of previous eye surgery ,to have indication of laser therapy,corticosteroid therapy,pregnancy,

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

1

Active Comparator group

Description:

Oral Amoxicillin Capsule Metronidazole Tablet Omeprazole Capsule

Treatment:

Drug: omeprazole, Amoxicillin, metronidazole

2

No Intervention group

Description:

No medical treatment