Effect of Hemifacial Spasm on Intraocular Pressure Measurement

Medipol University

Status: Completed

Conditions: Intraocular Pressure; Hemifacial Spasm

Treatments: Other: effect of hemifacial spasm on intraocular pressure

Study type: Observational

Funder types: Other

Identifiers

NCT03390803

02-115621

Details and patient eligibility

About

Twenty-four consecutive patients with Hemifacial spasm and 25 age and gender-matched randomly selected eyes of healthy volunteers underwent corneal pachymetry and intraocular pressure measurements using Goldmann Applanation Tonometer and non-contact tonometer. An interval of 15 minutes was maintained between Goldmann Applanation Tonometer and non-contact tonometer measurements. Intraocular pressure measurements were performed before (during hemifacial spasm) and 2 weeks after Botox injections in Hemifacial spasm patients and in healthy volunteers without Botox injections. All the measurements with Goldmann Applanation Tonometer were carried out by a single physician while those with the non-contact tonometer were done by another physician who was masked to the results of the Goldmann Applanation Tonometer. All measurements were taken between 10:00 and 11:00 a.m.

Enrollment: 49 patients

Sex: All

Ages: 40 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with hemifacial spasm

Exclusion criteria

• Subjects will be excluded if they have allergies to botulinum toxin or any component of the drug, previous eyelid, refractive or intraocular surgery, any abnormality preventing reliable tonometry in either eye, strabismus, contact lens wear, pregnancy, glaucoma, ocular hypertension and patients using agents that could interfere with neuromuscular transmission.

Trial design

49 participants in 2 patient groups

patients with hemifacial spasm

Treatment:

Other: effect of hemifacial spasm on intraocular pressure

healthy control subjects

Treatment:

Other: effect of hemifacial spasm on intraocular pressure