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About
The experimental approach in this study intends to investigate the role of hepatic glycogen content on nocturnal regulation of endogenous glucose production including the relative contributions of glycogenolysis and gluconeogenesis and the extent to which this differs between subjects with type 2 diabetes and subjects without diabetes. Both participants with type 2 diabetes and participants without diabetes will be studied after consuming either a low carbohydrate (no glycogen loading) or high carbohydrate (glycogen loading) diet.
Full description
Physiology study for looking at glycogen loading vs non loading in improving nightime glucose tolerance by increasing glycogen in liver and resulting higher glycogenolysis at night.
Enrollment
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Volunteers
Inclusion criteria
Age 30-75
BMI 20-35kg/m^2
Participants with type 2 diabetes:
Exclusion criteria
Pregnancy or breast feeding
Morbidities precluding participation
Participants with type 2 diabetes:
Participants without diabetes:
Primary purpose
Allocation
Interventional model
Masking
34 participants in 2 patient groups
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Data sourced from clinicaltrials.gov
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