Effect of High Flow Nasal During Exercise in COPD Patients (AiRehab)

Groupe Hospitalier du Havre

Status: Completed

Conditions: COPD Exacerbation

Treatments: Device: High Flow nasal cannula

Study type: Interventional

Funder types: Other

Identifiers

NCT03058081

2016-A01325-46

Details and patient eligibility

About

Early pulmonary rehabilitation is recommended after an episode of severe exacerbation of chronic obstructive pulmonary disease (COPD). However, its implementation is challenging particularly as regard exercise training. High flow ventilation in reducing work of breathing and dyspnea may improve exercise tolerance. The aim of this study is to carry out the acute effect of high flow nasal cannula on exercise endurance in post-exacerbation copd patients

Enrollment: 19 patients

Sex: All

Ages: 35 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• a diagnosis of COPD

Exclusion criteria

• exercise contraindication Any musculoskeletal problems, cardiovascular or neurological comorbidities that limits exercise.
• pH < 7,35
• Body temperature > 38°C
• cardiac frequency > 100 bpm at rest
• systolic blood pressure < 100 mmHg
• exacerbation during the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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19 participants in 2 patient groups

High Flow Nasal Test

Experimental group

Description:

Patients will perform one Constant Work-Rate Exercise Test at 80% of maximum workload with High Flow Nasal at 60L/min (with or without additional oxygen)

Treatment:

Device: High Flow nasal cannula

Control Test

No Intervention group

Description:

Patient will perform one Constant Work-Rate Exercise Test at 80% of maximum workload on room air or with oxygen supplementation