Effect of High Intensity Interval Exercise Training in Patients With Allergic Rhinitis

Chulalongkorn University

Status: Completed

Conditions: Allergic Rhinitis

Treatments: Other: High-intensity interval training group (HIIT); Other: Sedentary control group (CON); Other: Moderate continuous training group (MCT)

Study type: Interventional

Funder types: Other

Identifiers

NCT06543251

EX PHYSIO SPSC 11

Details and patient eligibility

About

The objective of this study was to compare the effects of training between high-intensity interval training and moderate continuous exercise training on the pulmonary function, respiratory muscle strength, symptoms of patients with allergic rhinitis, cytokines, and oxidative stress in patients with allergic rhinitis.

Full description

36 patients with allergic rhinitis were divided into 3 groups, 12 people per group: the control group (CON), the group with high-intensity interval training at a ratio of 1:2 (HIIT) and the group with moderate continuous training (MCT), 3 days per week, over a total period of 12 weeks. Before and after the experiment, lung function, respiratory muscle strength, allergic rhinitis symptoms, nasal blood flow rate, peak nasal inspiratory flow, nitric oxide levels, cytokines and quality of life were measured and used for statistical analysis.

Enrollment: 36 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A patient with allergic rhinitis who underwent a skin prick test and received a positive result.
• Patients with persistent allergic rhinitis, male and female, with symptoms of nasal congestion, sneezing, nasal itching, and runny nose for more than 4 days per week, and an average score of 7 or more in the past week using the allergic rhinitis symptom assessment questionnaire.
• stopped taking all medicine before the study such as antihistamine for 3 days, oral steroid and nasal steroid for at least 2 weeks and leukotriene receptor antagonist for at least a week prior to the study
• had no exercise program, non-smoking and without any food supplementation for at least 6 months prior to the start of the study
• Must not have other respiratory diseases such as bronchitis, pertussis, pneumonia, pneumonitis, aspergilloma, tuberculosis, asthma, lung cancer, emphysema, etc.
• Have a body mass index (BMI) between 18.5 and 24.9 kg/m².
• Complete the Physical Activity Readiness Questionnaire (PAR-Q+) by answering "no" to all questions.

Exclusion criteria

• There is an unforeseen circumstance, such as an illness, that prevents participation in the research.
• Less than 80% of the research was completed.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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36 participants in 3 patient groups

High-intensity interval training group (HIIT)

Experimental group

Description:

the group with high-intensity interval training at a ratio of 1:2 (HIIT) 3 days per week, over a total period of 12 weeks.

Treatment:

Other: High-intensity interval training group (HIIT)

Moderate continuous training group (MCT)

Experimental group

Description:

the group with moderate continuous training, 3 days per week, over a total period of 12 weeks.

Treatment:

Other: Moderate continuous training group (MCT)

Sedentary control group (CON)

Other group

Treatment:

Other: Sedentary control group (CON)