Effect of High Protein Diet on Cardiovascular Diseases Risk Factors Among Overweight and Obese Children

Isfahan University of Medical Sciences

Status and phase: Completed; Phase 3

Conditions: Body Mass Index Quantitative Trait Locus 7 Disorder; Tangier Disease

Treatments: Other: nutrition intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT01886482

high protein diet in childhood

Details and patient eligibility

About

The investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children.

Full description

Background: Studies regarding the effects of high protein (HP) diet on cardiovascular (CVD) risk factors have reported contradictory results.

Objective: In present study, the investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children.

Design: In this randomized controlled trial, the investigators recruited 50 overweight and obese women, aged 6-11years into HP or control energy restricted diets for 10 weeks (protein, carbohydrate, fat: 25%, 45%, 30% vs. 15%, 55%, 30%, respectively). Total protein amount, divided to animal and plant sources in 50%-50% and animal sources distributed (half/half) between meats and dairy products. Fasting blood samples, lipid profile, systolic and diastolic blood pressure and anthropometric measurements were measured based on the standard guidelines.

Enrollment: 50 patients

Sex: All

Ages: 6 to 11 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI > 85th age of 6-11 years
• no history of chronic diseases
• no taken medications

Exclusion criteria

• do not prescribe their diet
• mental retardation

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

nutrition intervention

Active Comparator group

Description:

high protein diet

Treatment:

Other: nutrition intervention

no intervention

No Intervention group

Description:

control diet