Effect of HIV Protease Inhibitor Drugs on Glucose and Insulin Metabolism

Bristol-Myers Squibb (BMS)

Status and phase: Completed; Phase 1

Conditions: HIV Infections

Treatments: Drug: Atazanavir/Ritonavir/Lopinavir/ritonavir

Study type: Interventional

Funder types: Industry

Identifiers

NCT00135434

AI424-130

Details and patient eligibility

About

This study examined the effects of two commonly prescribed HIV drugs on the way the body metabolizes glucose, insulin and fat.

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Healthy volunteers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)