Effect of Home Exercise Program on Various Parameters in Patients With Multiple Sclerosis

Muğla Sıtkı Koçman University

Status: Completed

Conditions: Autoimmune Disorder; Telerehabilitation; Multiple Sclerosis; Exercise Program

Treatments: Other: Multiple Sclerosis Quality of Life; Other: Berg Balance Test; Other: Time up and go- 25 steps walking test; Other: Fatigue Severity Scale; Other: Beck Depression and Anxiety Scale; Other: Brief International Cognitive Assessment for MS (BICAMS)

Study type: Interventional

Funder types: Other

Identifiers

NCT05447143

200301

Details and patient eligibility

About

Multiple Sclerosis (MS) is a chronic, inflammatory, neurodegenerative, and autoimmune disease that progresses with progressive neurological dysfunction and affects the central nervous system. A multidisciplinary rehabilitation approach is crucial in the systematic and supportive treatment of MS. Exercise training is a therapeutic approach that minimizes functional capacity loss and slows progression in MS. Randomized controlled studies have shown that exercise training improves physical fitness, reduces motor fatigue, and improves the quality of life and psychological state in individuals with MS.

When the literature is examined, it is seen that popular exercises such as pilates, yoga, and Tai-Chi are used in addition to aerobics, strengthening, endurance, and stretching exercises in the treatment of individuals with MS. In order to eliminate the economic burden, which is one of the exercise barriers of individuals, and to gain exercise habits, home exercise programs should be expanded. When the literature is examined, it is emphasized that the importance of home exercise programs is emphasized, and it is very important in the treatment of patients who cannot attend an exercise program, especially by going to any center for various reasons. However, there is little information on the effectiveness and content of home exercise programs in patients with MS. From this point of view, this study is capable of supporting the missing part of the literature.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. To be between the ages of 18-65
2. Being diagnosed with MS according to McDonald criteria
3. Having an EDSS score between 0-5.5
4. Being in the Relapsing Remitting class as a clinical subtype of MS
5. Not having any nervous system pathology other than MS
6. Not having an MS attack in the last 1 month
7. To ensure full cooperation and adaptation throughout the study.

Exclusion criteria

1. Being in an exacerbation period
2. To have participated in a regular physical activity program in the last 6 months
3. Having an orthopedic, cardiopulmonary or psychiatric disease that prevents exercise
4. Continuing another exercise therapy
5. Not volunteering to participate in the study
6. Having problems with reading comprehension

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 3 patient groups

Control Group (CG)

Other group

Description:

The control group will be queued to be included in the exercise program and participants' routine treatment will continue.

Treatment:

Other: Multiple Sclerosis Quality of Life

Other: Fatigue Severity Scale

Other: Beck Depression and Anxiety Scale

Other: Brief International Cognitive Assessment for MS (BICAMS)

Other: Berg Balance Test

Other: Time up and go- 25 steps walking test

Video Group (VG)

Experimental group

Description:

The exercise will be given as a video and participants will be asked to continue the exercises for 8 weeks, 3 days a week. Patients will be contacted by phone every week to ask if participants have any problems with the exercise program and their compliance.

Treatment:

Other: Multiple Sclerosis Quality of Life

Other: Fatigue Severity Scale

Other: Beck Depression and Anxiety Scale

Other: Brief International Cognitive Assessment for MS (BICAMS)

Other: Berg Balance Test

Other: Time up and go- 25 steps walking test

Brochure Group (BG)

Experimental group

Description:

Exercise will be given as a brochure and participants will be asked to continue the exercises given for 8 weeks, 3 days a week. Visual feedback will be provided by asking participants to mark the exercise tracking chart on the exercise brochures.

Treatment:

Other: Multiple Sclerosis Quality of Life

Other: Fatigue Severity Scale

Other: Beck Depression and Anxiety Scale

Other: Brief International Cognitive Assessment for MS (BICAMS)

Other: Berg Balance Test

Other: Time up and go- 25 steps walking test