Effect of Honey and Dexamethason on Extraction Healing

Al-Azhar University

Status and phase: Completed; Early Phase 1

Conditions: Impacted Third Molar Tooth

Treatments: Drug: Honey; Drug: Dexamethasone and honey; Drug: Dexamethasone; Drug: Normal saline

Study type: Interventional

Funder types: Other

Identifiers

NCT04848259

Impaction

Details and patient eligibility

About

Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated

Full description

Patient with impacted lower third molar will be selected to this study agording to agent applied preoperative. Group 1 will receive topical honey and Group 2 will receive IV dexamethason. After surgical removal of impacted tooth under local anesthesia postoperative pain mouth opening, and swelling will be evaluated

Enrollment: 80 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• impacted 3rd molar
• healthy patient No smoking

Exclusion criteria

• history of smoking Medical disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 4 patient groups, including a placebo group

Control

Placebo Comparator group

Description:

No drug given before surgery

Treatment:

Drug: Normal saline

Dexamethason

Active Comparator group

Description:

Dexamethason will be given IV before surgery

Treatment:

Drug: Dexamethasone

Natural honey

Active Comparator group

Description:

Honey will be placed locally after impaction removal

Treatment:

Drug: Honey

Dexamethason and natural honey

Active Comparator group

Description:

Dexamethason will be given IV before surgery and Honey will be placed locally after impaction removal

Treatment:

Drug: Dexamethasone and honey