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The investigators are studying the effects of Hyperglycemia on vascular function and insulin sensitivity on healthy adults
Full description
The investigators will study 22 healthy subjects (18-35 yrs) four times as follows:
The sequence of admissions will be assigned randomly. The investigators will assess function in conduit (pulse wave velocity-PWV, augmentation index-AI and flow-mediated dilation-FMD), resistance (post-ischemic flow velocity-PIFV) and heart and skeletal muscle microvascular (contrast enhanced ultrasound-CEU) vessels.
This work will:
a) identify whether vascular stiffness and indices of NO action are impaired throughout the arterial tree with hyperglycemia.
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15 participants in 4 patient groups
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Data sourced from clinicaltrials.gov
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