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Effect of IATP on Cognitive Functioning in Anxious Older Adults.

T

The Hong Kong Polytechnic University

Status

Completed

Conditions

Anxiety Symptoms

Treatments

Other: Integrated Attention Training Program (IATP)
Other: Health Education

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Older adults with anxiety symptoms was found to be associated with greater risk of dementia. Interventions targeting signs as early as in the pre-symptomatic phase could be most effective in early prevention of dementia. On reviewing the identified non-pharmacological interventions, integrated attention training program (IATP) is proposed to target older adults with anxiety symptoms in Hong Kong.

Full description

Older adults with anxiety disorders or symptoms are not in the consideration of management for dementia prevention. However, the condition is found to be associated with profound negative subsequent decline on both functioning and cognition. While epidemiological studies reported high prevalence in older population, its symptoms are often overlooked in the presence of other age-related diseases in the community as well as among the health professionals. It is expected that cognitive and functional disabilities secondary to this condition will pose a significant burden to the existing healthcare system. Therefore, targeting anxious older adults for early intervention may help to cut healthcare costs and to ensure proactive dementia prevention in the long run. The current proposed intervention intends to attenuate the trajectory of cognitive decline at a very early stage and enhance existing cognitive function to delay the onset of dementia.

This study aims to explore whether the use of integrated attention training program (IATP) could improve cognitive performance and functioning in older adults with anxiety symptoms. In particulars, we aim

  1. To examine the cognitive effect of 4 week integrated attention training program (I) and health education (C) in older adults with anxiety symptoms.
  2. To examine the 4 week integrated attention training program (I) and health education (C) in alleviating mood symptoms in older adults with anxiety symptoms.
  3. To examine the acceptability and adherence of the proposed intervention.

Enrollment

48 patients

Sex

All

Ages

60 to 90 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  1. Older adults aged 60 - 90 years; and
  2. Presence of subjective memory complaints as measured by memory inventory for the Chinese; and
  3. Anxiety symptoms as measured by Hamilton Anxiety Scale (HAM-A) with a score of 18 or above (indicated as mild anxiety symptoms).

Exclusion criteria

  1. DSM-5 diagnosis of either Major Neurocognitive Disorder due to AD, or Major Vascular Neurocognitive Disorder with small vessel disease. This would include satisfying criteria for significant cognitive decline in at least one of six areas of cognition (memory, perceptual-motor, complex attention, language, executive function and social cognition), and with clinical or neuroimaging features indicative of either AD or small vessel disease; or;
  2. Clinical dementia rating larger than or equal to 0.5; or
  3. Clinically depressed as assessed by Hamilton Depression Rating Scale with a score of 20 or higher; or
  4. Past history of major depressive episode, bipolar affective disorders or psychosis; or
  5. Physical frailty that may affect attendance to training sessions; or
  6. Currently on psychotropic or other medications know to affect cognition (e.g., benzodiazepines, anti-dementia medication, etc.); or
  7. Participants in other cognitive training or intervention for brain health during the study period; or
  8. Presence of major neurological deficit including history of stroke, transient ischemic attack or traumatic brain injury; or
  9. Significant communicative impairment.

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

48 participants in 2 patient groups, including a placebo group

Integrated Attention Training Program
Experimental group
Description:
The intervention group (I) will receive "integrated attention training program (IATP)" on a variety of structured attention tasks by an intervention instructor. It is considered to be simple and safe but effective enough for cognitive health promotion.
Treatment:
Other: Integrated Attention Training Program (IATP)
Health Education
Placebo Comparator group
Description:
The control group (C) will receive health educational sessions on health concerns and physical diseases commonly found in old age during the invention period.
Treatment:
Other: Health Education

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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