Effect of Increased BMI on Efficacy of Labor Analgesia

Mariah Arif

Status: Completed

Conditions: Neuraxial Analgesia; Labor Analgesia

Treatments: Procedure: Neuraxial Analgesia; Procedure: Neuraxial analgesia

Study type: Observational

Funder types: Other

Identifiers

NCT07367347

MRC-01-24-875

Details and patient eligibility

About

This study seeks to identify the most effective neuraxial technique for labor analgesia in Class III parturient

Full description

This retrospective cohort study collected data on eligible participants from the electronic medical records.

Enrollment: 9,000 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age > or equal to 18 years
• BMI ≥ 40 kg/m²
• Gestational age ≥ 28 weeks

Exclusion criteria

• Age < 18 years
• BMI < 40 kg/m²
• History of venous thromboembolism or arterial disease (e.g., DVT, PE, angina, MI, or stroke)
• Severe active lung, cardiovascular, renal, or liver disorders; autoimmune disease; or hemoglobinopathies
• Hereditary or acquired thrombophilia (e.g., Factor V Leiden mutation or antithrombin deficiency)
• In utero fetal demise (IUFD)
• Failed operative vaginal delivery
• Cesarean for the second twin or multiple pregnancies (triplets or higher)
• IVF pregnancy
• Intraoperative bleeding>1500mL
• Emergency cesarean section (Category I)
• Presence of large uterine fibroid ≥10 cm.

Trial design

9,000 participants in 1 patient group

Class III obese parturient

Description:

Class III obese parturient receiving neuraxial analgesia

Treatment:

Procedure: Neuraxial analgesia