Effect of Increased Oxygenation in the Air During Endurance Training in Stable Angina Pectoris Patients

Norwegian University of Science and Technology

Status: Completed

Conditions: Angina Pectoris

Treatments: Behavioral: Normoxic interval training; Behavioral: Hypoxic interval training

Study type: Interventional

Funder types: Other

Identifiers

NCT00184444

094-2004

Details and patient eligibility

About

The study investigates whether endurance training breathing 100% oxygen gives a additional improvement of maximal oxygen uptake in stable Angina Pectoris patients, compared to training without extra oxygen supplementation. In addition work economy, stroke volume and cardiac perfusion is measured.

The hypothesis of the study is that increased oxygenation of the air increases performance, stroke volume, work economy and cardiac perfusion.

Enrollment: 25 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• stable angina pectoris age 18-75

Exclusion criteria

• unstable angina pectoris
• Limitations to exercise other than coronary artery disease
• Participants in other study interventions

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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25 participants in 2 patient groups

Hypoxic Interval training

Experimental group

Description:

4 x 4 minutes interval training with 100% oxygenated air

Treatment:

Behavioral: Hypoxic interval training

Normoxic interval training

Experimental group

Description:

4 x 4 minutes interval training in normoxic air

Treatment:

Behavioral: Normoxic interval training