Effect of Injection Duration of Fascial Plane Blocks on Block Success

Bursa Yüksek İhtisas Education and Research Hospital

Status: Not yet enrolling

Conditions: Nerve Block

Treatments: Drug: Group C; Drug: Group T; Drug: Group O

Study type: Interventional

Funder types: Other

Identifiers

NCT07096765

2024-ТВЕK 2025/07-05

Details and patient eligibility

About

This prospective observational study aims to evaluate the impact of injection duration during fascial plane blocks on block success and analgesic efficacy in patients undergoing laparoscopic cholecystectomy. The hypothesis is that shorter injection durations increase injection pressure, potentially limiting local anesthetic spread, while longer durations facilitate broader anesthetic distribution.

Full description

Fascial plane blocks involve injecting local anesthetics between two anatomical fascial layers, with analgesia achieved by anesthetic diffusion through the fascial plane. However, anesthetic spread may vary significantly based on injection technique, speed, and pressure. This study hypothesizes that injection duration directly influences injection pressure, local anesthetic distribution, and consequently, the extent of sensory blockade and analgesia.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Laparoscopic cholecystectomy surgery
• Patients with ASA (American Society of Anaesthetists) scores I and III will be included.

Exclusion criteria

• Uncontrolled Arterial Hypertension
• Uncontrolled Diabetes Mellitus,
• Mental retardation
• Antidepressant use
• Metabolic disorders
• Bleeding diathesis
• Patients with a body mass index above 30

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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100 participants in 3 patient groups

Conventional

Active Comparator group

Description:

During the fascia block application, the injection will be administered using the conventional method without any specific time limit.

Treatment:

Drug: Group C

One-minute injection

Active Comparator group

Description:

During the fascia block application, the injection will be administered within 1 minute.

Treatment:

Drug: Group O

Two-minute injection

Active Comparator group

Description:

During the fascia block application, the injection will be administered within 2 minutes.

Treatment:

Drug: Group T