Effect of Inspiratory Muscle Training in Cognition

University of West Attica

Status: Enrolling

Conditions: Mild Cognitive Impairment (MCI)

Treatments: Other: Usual Care; Other: Inspiratoty Muscle training

Study type: Interventional

Funder types: Other

Identifiers

NCT07146373

27134

Details and patient eligibility

About

The goal of this clinical trial is to examine the effect of a respiratory muscle strengthening program on the cognitive and physical functioning of patients with neurocognitive disorders (Mild Cognitive Impairment) or those predisposed to them.

The main questions that aims to answer are:

1. Is Inpsiratory Muscle Training (IMT) feasible in people with mild cognitive impairement?
2. Could Inspiratory Muscle Training (IMT) improve congitive function in people with mild cognitive impairement?
3. Could Inspiratory Musclre training improve physical function in this population?

Participants will be:

1. < 60 age or > 90 age
2. MMSE (Mini Mental State Examination) score ≤ 28 and ≥ 18 and follow a high intensity IMT program along with a physical - cognitive program. or just the physical - cognitive program.

Enrollment: 76 estimated patients

Sex: All

Ages: 60 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• MMSE (Mini Mental State Examination) score ≤ 28 και ≥ 18
• stable treatment related to medication

Exclusion criteria

• MMSE score < 18 και > 28
• psychological disorder
• any contraindication to physical training

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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76 participants in 2 patient groups

Inspiratory Muscle Training

Experimental group

Description:

IMT that consists of 5set/6 breaths at 50-60% of Maximal Inspiratory Pressure, 5 session per weak for 3 months. Physical and Cognitive training

Treatment:

Other: Inspiratoty Muscle training

Control

Active Comparator group

Description:

Physical and cognitive training

Treatment:

Other: Usual Care