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Effect of Intake of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on Blood Cholesterol.

H

Hanyang University

Status

Completed

Conditions

Hyperlipidemia

Treatments

Dietary Supplement: Placebo
Dietary Supplement: Citron peel extract

Study type

Interventional

Funder types

Other

Identifiers

NCT03332641
HYI-17-060-1

Details and patient eligibility

About

This study was conducted to investigate the effects of daily supplementation of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on improvement of Blood Cholesterol.

Full description

This study was a 12 weeks, randomized, double-blind, placebo-controlled human trial. Twenty subjects were randomly divided into Citron(Citrus Junos Siebold ex Tanaka) Peel Extract or a placebo group. Blood cholesterol profiles before and after the intervention.

Enrollment

70 patients

Sex

All

Ages

19 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Age 19-75 years with Total cholesterol 200-239 mg/dL

Exclusion criteria

  • Lipid lowering agent within past 6 months
  • Severe cardiovascular disease(Mvodardial infarction, stroke, etc)
  • Renal disease(Heredity hyperlipidemia, Acute/Chronic renal failure, Nephrotic syndrome, ect)
  • Cancer, Respiratory organ disease(Asthma, Chronic obstructive pulmonary disease)
  • Diabetes mellitus
  • Allergic or hypersensitive to any of the ingredients in the test products
  • History of disease that could interfere with the test products or impede their absorption
  • Under antipsychotic drugs therapy within past 2 months
  • History of alcohol or substance abuse
  • Participation in any other clinical trials within past 2 months
  • Laboratory test by show the following results
  • Pregnancy or breast feeding
  • Not Contraception(except: Surgery for female infertility)

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

70 participants in 2 patient groups, including a placebo group

Citron peel Extract
Experimental group
Description:
Citron peel extract for 12 weeks
Treatment:
Dietary Supplement: Citron peel extract
Placebo
Placebo Comparator group
Description:
Placebo for 12 weeks
Treatment:
Dietary Supplement: Placebo

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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