Effect of Intake of Pyrus Pyrifolia Var. Culta(Makino) NaKai Peel Extract on Body Fat and Blood Lipid.

Hanyang University

Status and phase

Unknown

Phase 3

Phase 2

Conditions

Obesity

Treatments

Dietary Supplement: Pyrus pyrifolia var. culta(Makino) NaKai peel extract

Dietary Supplement: Placebo

Study type

Interventional

Funder types

Other

Identifiers

NCT02742688

GFB-BF-PE

Details and patient eligibility

About

The investigators performed a 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Pyrus pyrifolia var. culta(Makino) NaKai peel extract on decrement of body fat. The investigators measured decrement of body fat parameters , including Body Fat Mass, Percent Body Fat, weight and BMI(body mass index), and monitored their blood pressure.

Enrollment

70 patients

Sex

All

Ages

19 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Males and females 19-65 years old
BMI(body mass index) 25~29.9 kg/m^2 or WC(Waist Circumference) ≥ 90(men), WC ≥ 85(women)
Able to give informed consent

Exclusion criteria

BMI(body mass index) ≥ 30 kg/m^2
Significant variation in weight(more 10%) in the past 3 months
Allergic or hypersensitive to any of the ingredients in the test products
History of reaction to any of the test products or of gastrointestinal diseases such as Crohn's disease or gastrointestinal surgery
History of alcohol or substance abuse
Participation in any other clinical trials within past 2 months
Laboratory test, medical or psychological conditions deemed by the investigators to interfere with successful participation in the study
Pregnant or lactating women etc.