Effect of Interscalene Block on Ventilatory Function (KTBIS)

Pierre and Marie Curie University

Status and phase

Completed

Phase 4

Conditions

Block

Anesthesia Morbidity

Respiratory Depression

Treatments

Drug: ropivacaine 2 mg/ml

Study type

Interventional

Funder types

Other

Identifiers

NCT01740453

KTBIS-2012-V1

Details and patient eligibility

About

Interscalene block with local anesthetic impairs ventilation (unilateral diaphragmatic dysfunction). Single injection of local anesthetic induced transitory dysfunction (< 24h). The investigators hypothesized that continuous interscalene block would prolonged ventilatory impairment

Full description

Unilateral pulmonary dysfunction occured after interscalene block due to phrenic nerve paralysis. This reduction induced vital capacity alteration and peek flow reduction.Several studies analysed dysfunction recovery duration after single injection using short (lidocaine)or intermediate (ropivacaine, bupivacaine)local anesthetic drug. Because continuous infusion prolonged block duration, phenic nerve may be also prolonged. However no study with continuous interscalene infusion have been performed for this dysfunction.

Enrollment

70 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

surgery : scheduled for elective shoulder surgery
available for 1 month of follow up
physical status : 1, 2, 3

Exclusion criteria

body mass index > 35
contraindication for interscalene block (local sepsis, bleeding, allergy, peripheral neuropathy)
vital capacity less than 1.5 liters
cardiac or renal insufficiency
physical status >3, pregnant, weigh less than 50 kg