Effect of Intraocular Tamponade on Visual Perception

Benha University

Status: Enrolling

Conditions: Retinal Detachment; Glaucoma; Optic Neuropathy

Treatments: Procedure: Vitrectomy operation; Diagnostic Test: Electroretinogram

Study type: Interventional

Funder types: Other

Identifiers

NCT05543018

RC-10-22

Details and patient eligibility

About

Intraocular tamponade used in vitrectomy operations may affects retinal function in various mechanisms.

Full description

Various intraocular tamponade are being used in vitrectomy operations as gases, fluids and silicon oil. The effects of these intraocular tamponade may affects the final visual outcome of the surgery.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• primary retinal detachment patients.
• patients eligible for 23 gauge pars-plana vitrectomy operation.

Exclusion criteria

• patients with axial length more than 30 millimeter that may have severe chorioretinal degenerations that may affects retinal function.
• patients with macular diseases that may affects final visual outcome as macular holes and choroidal neovascular membranes.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 3 patient groups

Silicon oil group

Active Comparator group

Description:

Patients diagnosed with retinal detachment and undergone vitrectomy operation with silicon oil tamponade.

Treatment:

Procedure: Vitrectomy operation

Diagnostic Test: Electroretinogram

Air tamponade

Active Comparator group

Description:

Patients diagnosed with retinal detachment and undergone vitrectomy operation with air tamponade.

Treatment:

Procedure: Vitrectomy operation

Diagnostic Test: Electroretinogram

Non-expansile gas

Active Comparator group

Description:

Patients diagnosed with retinal detachment and undergone vitrectomy operation with non-expansile gas tamponade (sulfur hexafluoride).

Treatment:

Procedure: Vitrectomy operation

Diagnostic Test: Electroretinogram