Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications

Zhejiang University

Status: Completed

Conditions: Spinal Fusion; Pulmonary Complication; Transfusion

Treatments: Procedure: transfusion

Study type: Observational

Funder types: Other

Identifiers

NCT05661838

2022-0968

Details and patient eligibility

About

Elective spine surgery is associated with a high incidence of perioperative complications, including peri- and postoperative pulmonary complications (PPCs), which occur in nearly 4% of patients. More than 40% of all deaths after elective spine surgery are attributed to PPCs. However, whether it influences risk of other PPCs is unclear.

Enrollment: 272 patients

Sex: All

Ages: 9 to 82 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients were included if they underwent elective spine surgery (e.g. multi-segmental thoracic, lumbar, or thoracolumbar spine surgery) at the Second Hospital of Zhejiang University School of Medicine from August 1, 2013 to October 31, 2020

Exclusion criteria

• combined anterior-posterior surgery
• growth rod adjustment surgery
• spinal tumor.
• surgery took fewer than 3 hours.

Trial design

272 participants in 2 patient groups

non-PPCs group

Description:

Patients without PPCs (Pleural effusion, Pulmonary atelectasis, Pulmonary infection)

Treatment:

Procedure: transfusion

PPCs group

Description:

Patients with PPCs (Pleural effusion, Pulmonary atelectasis, Pulmonary infection)

Treatment:

Procedure: transfusion