Effect of Intraoperative Music on Inflammatory Response in Donor Hepatectomy

Istinye University

Status: Completed

Conditions: Music; Hepatectomy; Stress Response; Transplantation

Treatments: Other: music; Other: no music

Study type: Interventional

Funder types: Other

Identifiers

NCT06166186

anestezi3

Details and patient eligibility

About

It has been reported that non-pharmacological methods can be used as an alternative in addition to pharmacological methods to reduce pain, anxiety, stress and inflammatory response that begins with the surgical incision in the intraoperative period and continues throughout the operation. It has been reported that music can be used as an alternative non-pharmacological method to reduce pain and anxiety in the perioperative period, as well as surgical stress and the related stress response.

The aim of this study is to test the hypothesis that music used as a non-pharmacological method in the intraoperative period can reduce inflammatory response in living donor hepatectomy.

Enrollment: 61 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing donor hepatectomy
• American Society of Anesthesiologists class 1 to 2
• Ability to consent

Exclusion criteria

• American Society of Anesthesiologists greater than 2
• Documented or known sensitivity to any drug to be used in the study.
• Patient with immunosuppressant/ cytotoxic/ steroid therapy.
• not understand the aim and objectives of the study

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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61 participants in 2 patient groups

Music Group

Active Comparator group

Description:

Music will be delivered via headphones intraoperatively. Blood samples will be collected as per the protocol.

Treatment:

Other: music

Control Group

Active Comparator group

Description:

Headphones will be applied but no music will be played intraoperatively. Blood samples will be collected as per the protocol.

Treatment:

Other: no music