Effect of Intraperitoneal Nebulisation of Magnesium Sulphate for Analgesia Following Laparoscopic Cholecystectomy

B.P. Koirala Institute of Health Sciences

Status and phase: Unknown; Phase 4

Conditions: Postoperative Pain

Treatments: Drug: intraperitoneal nebulisation of magnesium sulphate

Study type: Interventional

Funder types: Other

Identifiers

NCT01542697

698/067/068

Details and patient eligibility

About

intraperitoneal nebulisation with magnesuim sulphate will reduce post operative pain and analgesic consumption in postoperative period following laparoscopic cholecystectomy.

Full description

Sixty patients undergoing laparoscopic cholecystectomy belonging to American Society of Anaesthesiologist (I-II) of age 18-65 yrs will be enrolled.Group one (n=30) will receive 1.5 gm magnesium sulphate diluted in 3ml of normal saline and group 2 (n=30) will receive 5 ml of NS.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: ASA I-II

Exclusion Criteria: history of

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups, including a placebo group

Magnesium sulphate

Active Comparator group

Description:

intraperitoneal nebulisation of 1.5 gm of magnesium sulphate with 2 ml of normal saline at the end of surgery before closure

Treatment:

Drug: intraperitoneal nebulisation of magnesium sulphate

normal saline

Placebo Comparator group

Description:

intraperitoneal nebulisation of 5 ml of normal saline after end of surgery before closure

Treatment:

Drug: intraperitoneal nebulisation of magnesium sulphate