Effect of Intravenous Dexmedetomidine Versus Dexamethasone for Management of Repound Pain After Supraclavicular Brachial Plexus Block

Assiut University

Status and phase: Not yet enrolling; Phase 1

Conditions: Trauma Injury

Treatments: Drug: Dexmedetomidine injection

Study type: Interventional

Funder types: Other

Identifiers

NCT06304909

2080278

Details and patient eligibility

About

Effect of intravenous dexmedetomidine versus dexamethasone for management of repound pain after supraclavicular brachial plexus block.

Enrollment: 111 estimated patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients between 20_60 years old

  • Patients with ASA clinical status I/II
  • Patients scheduled for peripheral nerve block for upper extremity surgery

Exclusion criteria

• 1. they refused to participate 2) had preexisting neuropathy of the surgical limb 3) hypersensitivity to amide anesthetic 4) significant pulmonary disease 5) coagulopathy 6) sepsis 7) infection at the block site 8) hypersensitivity to dexmedetomidine & dexamethasone

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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111 participants in 3 patient groups

Dexmedetomidine group will receive 0.5 mcg/kg

Experimental group

Treatment:

Drug: Dexmedetomidine injection

Dexamethasone group will receive 8mg/kg

Experimental group

Treatment:

Drug: Dexmedetomidine injection

Control group will receive equivalent volume of saline 0.9%.

Experimental group

Treatment:

Drug: Dexmedetomidine injection