Effect of Intravenous Dextrose on PONV in Patients Undergoing Gynecological Laparoscopy

Weifang Medical University

Status: Enrolling

Conditions: Postoperative Nausea and Vomiting

Treatments: Other: lactated ringers; Other: 5% glucose

Study type: Interventional

Funder types: Other

Identifiers

NCT05932160

2023YX104

Details and patient eligibility

About

This study is to explore the relationship between intravenous infusion of dextrose during emergence from anesthesia and the incidence of PONV in patients undergoing gynecology laparoscopy (GL).

Enrollment: 108 estimated patients

Sex: Female

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. ASA I or II;
2. Performing gynecologic laparoscopic procedures under general anesthesia;

Exclusion criteria

1. age <18 or >75
2. severe hypertension,diabetes mellitus, significant hepatic or renal disease
3. inability to follow protocol
4. refusal to participant

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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108 participants in 2 patient groups

Experimental group

Active Comparator group

Description:

Patients in the experimental group were infused intravenously with 5% dextrose (400 ml/h) in the PACU. The study outcomes were collected at three assessment periods, 0-0.5 h, 0.5-6 h, 6-24 h, after anesthesia by an independent investigator.

Treatment:

Other: 5% glucose

Control group

Active Comparator group

Description:

Patients in the control group were infused intravenously with ringer lactate solution (400 ml/h) in the PACU. The study outcomes were collected at three assessment periods, 0-0.5 h, 0.5-6 h, 6-24 h, after anesthesia by an independent investigator.

Treatment:

Other: lactated ringers