Effect of Intravenous Magnesium During Robot Assisted Prostatectomy

Ajou University School of Medicine

Status: Completed

Conditions: Prostatic Neoplasms

Treatments: Drug: Normal saline; Drug: Magnesium Sulfate

Study type: Interventional

Funder types: Other

Identifiers

NCT02833038

AJIRB-MED-CT4-16-074

Details and patient eligibility

About

The primary purpose of this study is to investigate the effect of intravenous magnesium on blood pressure after Trendelenburg position during robot assisted prostatectomy.

The secondary purpose of this study is to investigate the effect of intravenous magnesium on pain after robot assisted prostatectomy.

Enrollment: 60 patients

Sex: Male

Ages: 60 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Robot assisted prostatectomy

Exclusion criteria

• Allergy to magnesium
• Chronic pain
• Chronic opioid use
• Chronic NSAID use
• Renal dysfunction
• Liver dysfunction
• Cardiac arrythmia
• Seizure

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Magnesium group

Experimental group

Description:

Intravenous administration of Magnesium Sulfate

Treatment:

Drug: Magnesium Sulfate

Control group

Placebo Comparator group

Description:

Intravenous administration of normal saline

Treatment:

Drug: Normal saline