Effect of Isoflavone Supplementation Associated With Physical Exercise in the Health Parameters of Postmenopausal Women

Federal University of Uberlandia

Status: Completed

Conditions: Bloodpressure

Treatments: Other: Placebo; Other: isoflavone; Other: exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03008785

CAAE: 40622414.9.0000.5152

Details and patient eligibility

About

This study evaluate if 10 weeks of mixed exercise combined with isoflavones could have greater effects on climacteric symptoms, body composition and hydratation, lipidic and inflamatory profile than exercise alone in postmenopausal women. the participants will be randomly assigned to the group: placebo and exercise or 100mg of isoflavone and exercise.

Full description

Several endocrine metabolic changes occur during the climacteric period, due to the lack of estrogen and also by the aging process and some studies show that ingestion of isoflavones by postmenopausal women may have benefits. Theoretically the isoflavone potentiate the effects obtained during exercise

Enrollment: 32 patients

Sex: Female

Ages: 50 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy postmenopausal woman
• to be able to practice exercises on treadmill and weight exercises
• without physical complications that prevent the execution of physical exercises
• have no history of cardiovascular disease, diabetes, renal pathologies or hypertension

Exclusion criteria

• smokers
• use hormone therapy or isoflavone
• use drugs that interfere with lipid and antihypertensive metabolism

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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32 participants in 2 patient groups

group isoflavone and exercise

Experimental group

Description:

The isoflavone group received daily 100mg of isoflavones.

Treatment:

Other: isoflavone

Other: exercise

group placebo and exercise

Experimental group

Description:

The placebo group received 100mg containing starch of corn.

Treatment:

Other: exercise

Other: Placebo