Effect of Kefir on Appetite

TC Erciyes University

Status: Completed

Conditions: Appetitive Behavior

Treatments: Other: LGI-Milk Breakfast; Other: HGI-Kefir Breakfast; Other: LGI-Kefir Breakfast

Study type: Interventional

Funder types: Other

Identifiers

NCT03636217

not defined

Details and patient eligibility

About

This study aimed to determine the effect of kefir on appetite in healthy subjects. A randomized, single-blind, and 3-intervention crossover trial included 22 healthy and normal-weight (BMI 18.5-25 kg/m2) females aged 21-24 years. Participants were recruited to three test meals: an LGI-Milk, an LGI-Kefir, and an HGI-Kefir, with a one-week washout period. Appetite ratings were measured at 0, 15, 30, 60, 90, 120, 150, and 180 minutes. At the end of three hours, participants were served an ad libitum lunch meal. Then, the foods eaten at lunch were recorded and their energy and nutrient analysis was calculated.

Enrollment: 24 patients

Sex: Female

Ages: 21 to 24 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Normal-weight (BMI 18.5-25 kg/m2)
• Female
• 21-24 years

Exclusion criteria

• During the last three months, change more than 5 kg in body weight or following an energy-restricted diet
• Being a vegan
• Having any chronic diseases such as diabetes, hypertension, etc.
• Physician-diagnosed medications or conditions that influence metabolism
• Smoking
• Practicing endurance sports
• Having difficulties with swallowing/eating
• Lack of appetite
• Hypersensitivity for the foods understudy
• Pregnant or lactating

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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24 participants in 3 patient groups

LGI-Milk Breakfast

Experimental group

Description:

Low glycemic index and milk content (LGI-Milk) breakfast as a test meal

Treatment:

Other: LGI-Milk Breakfast

LGI-Kefir Breakfast

Experimental group

Description:

Low glycemic index and kefir content (LGI-Kefir) breakfast as a test meal

Treatment:

Other: LGI-Kefir Breakfast

HGI-Kefir Breakfast

Experimental group

Description:

High glycemic index and kefir content (HGI-Kefir) breakfast as a test meal

Treatment:

Other: HGI-Kefir Breakfast