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Effect of Kinesiotaping on Tremor in People With Parkinson's Disease

S

Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey

Status

Completed

Conditions

Tremor Associated With Tremor Dominant Parkinson's Disease
Tremor
PARKINSON DISEASE (Disorder)

Treatments

Behavioral: Home Exercise Program
Other: Sham Taping
Other: Therapeutic Kinesiotaping

Study type

Interventional

Funder types

Other

Identifiers

NCT07555847
PD-KT-RCT-2025

Details and patient eligibility

About

The goal of this clinical trial is to learn whether adding kinesiotaping to a strengthening and stretching home-exercise program can reduce hand tremor and improve hand function in people with Parkinson's disease. The study will also examine how true kinesiotaping compares with sham (placebo) taping and with exercise alone in improving tremor frequency, grip strength, fine motor skills, motor symptoms, daily living activities, and quality of life.

Adults aged 18-80 with Parkinson's disease and hand tremor will be randomly assigned to one of three groups:

Kinesiotaping + Exercise Group: Participants will receive therapeutic kinesiotaping applied to the forearm extensor muscles and wrist for 4 weeks (twice weekly), in addition to a home program of strengthening and stretching exercises.

Sham Taping + Exercise Group: Participants will receive a placebo taping without tension that does not target specific muscles, along with the same exercise program.

Exercise-Only Group: Participants will complete the same home-exercise program without any taping.

Researchers will compare the three groups to see whether kinesiotaping provides additional benefits beyond exercise and whether it performs better than sham taping. Tremor frequency will be measured using an Apple Watch device, and hand strength, dexterity, motor symptoms, and quality of life will be assessed using validated clinical scales.

Full description

Resting tremor is one of the main motor symptoms in Parkinson's disease and can significantly limit daily activities, fine motor skills, and upper-extremity function. This clinical trial is designed to evaluate whether adding therapeutic kinesiotaping to a home-based exercise program can reduce hand tremor and improve hand function. The study also aims to compare the effectiveness of true kinesiotaping with sham (placebo) taping and to determine whether either method provides additional benefit beyond exercise alone.

This randomized, controlled, three-arm clinical trial will include participants aged 18 to 80 years who have been diagnosed with Parkinson's disease and experience hand tremor. Participants will be randomly assigned to one of three groups: (1) Kinesiotaping + Exercise, (2) Sham Taping + Exercise, or (3) Exercise Only. All participants will receive a standardized home-exercise program that includes strengthening and stretching exercises targeting forearm muscles. The exercise program will be performed once daily for four weeks.

In the kinesiotaping group, therapeutic taping will be applied to the forearm extensor muscles and wrist using functional taping techniques with appropriate tension and directional application. This approach aims to enhance proprioceptive input, improve muscle activation, and reduce tremor amplitude. In the sham taping group, tape will be applied without therapeutic tension and without following muscle-fiber orientation, providing a placebo intervention. The control group will receive the exercise program only, without any taping.

Tremor severity and frequency will be assessed using accelerometer data from an Apple Watch worn on the affected wrist. Grip strength will be measured with a Jamar dynamometer, and hand dexterity will be evaluated using the Nine Hole Peg Test. Motor symptoms will be assessed with the MDS-UPDRS Part 3, and quality of life will be evaluated using the Parkinson's Disease Questionnaire (PDQ-39). Outcomes will be measured at baseline (T0), at the end of the 4-week intervention (T1), and two weeks after the end of treatment (T2).

The primary objective of this study is to determine whether kinesiotaping provides additional benefit in reducing hand tremor compared with exercise alone. Secondary objectives include evaluating improvements in hand function, changes in grip strength, changes in motor symptoms, and improvements in quality-of-life measures. Kinesiotaping is expected to support tremor control by enhancing proprioceptive feedback. The sham taping group is included to control for placebo effects and to distinguish the specific therapeutic contribution of true kinesiotaping.

This study aims to provide clinical evidence on the usefulness of kinesiotaping as an adjunct to exercise for managing tremor in individuals with Parkinson's disease. The three-arm design will allow clear comparison between true taping, sham taping, and exercise alone, helping to identify the unique effects of kinesiotaping.

Enrollment

45 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Diagnosis of idiopathic Parkinson's disease
  • Hoehn and Yahr stage 1-4
  • Presence of hand tremor
  • Mini-Mental State Examination (MMSE) score ≥ 23
  • Stable medical treatment for at least 3 months prior to enrollment and no planned changes during the study period
  • Age between 18 and 80 years
  • Ability to understand and provide written informed consent

Exclusion criteria

  • Diagnosis of essential tremor or tremor due to causes other than Parkinson's disease
  • Advanced motor impairment (severe bradykinesia or dyskinesia)
  • History of allergic reaction to kinesiotaping materials
  • Presence of other neurological disorders causing tremor (e.g., ALS, multiple sclerosis, cerebellar disorders)
  • Severe psychiatric disorders (e.g., major depression, psychosis, severe anxiety)

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

45 participants in 3 patient groups

Kinesiotaping + Exercise
Experimental group
Description:
Participants receive therapeutic kinesiotaping applied to the forearm extensor muscles and wrist twice weekly for 4 weeks, in addition to a daily home-based strengthening and stretching exercise program.
Treatment:
Other: Therapeutic Kinesiotaping
Behavioral: Home Exercise Program
Sham Taping + Exercise
Sham Comparator group
Description:
Participants receive sham taping without therapeutic tension and without following muscle-fiber orientation, applied twice weekly for 4 weeks, along with the same daily home-based exercise program
Treatment:
Other: Sham Taping
Behavioral: Home Exercise Program
Exercise Only
Active Comparator group
Description:
Participants complete the standardized daily home-based strengthening and stretching exercise program for 4 weeks, with no taping applied
Treatment:
Behavioral: Home Exercise Program

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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