Effect of Laparoscopic Ovarian Drilling on Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome

A

Ain Shams University

Status

Unknown

Conditions

PCOS

Treatments

Procedure: IVF/ICSI

Study type

Interventional

Funder types

Other

Identifiers

NCT03527979
rkamal

Details and patient eligibility

About

the polycystic ovarian syndrome is associated with an ovulation and infertility. recently the laparoscopic ovarian drilling has been used as surgical treatment for ovulation in women with polycystic ovarian syndrome, although its mechanism and outcomes are still unclear. this study is undertaken to evaluate the in vitro fertilisation outcomes in clomiphene-resistant women with PCOS who were treated with LOD.

Enrollment

88 patients

Sex

Female

Ages

25 to 35 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • age between 25 and 35
  • patients with established PCOS
  • history at least one year infertility
  • no response to clomiphene citrate for at least three cycles

Exclusion criteria

  • history of previous IVF/ICSI
  • chronic disease such as thyroid disorder and DM
  • infertility due to sever male factor
  • sever endometriosis
  • infertility due to uterine factor such as multiple fibroid
  • body mass index > 30

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

88 participants in 2 patient groups

PCOS women with history of LOD before IVF/ICSI
Active Comparator group
Treatment:
Procedure: IVF/ICSI
PCOS women without history of drilling
Active Comparator group
Treatment:
Procedure: IVF/ICSI

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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