Effect of Local Infiltration Anesthesia With Ropivacaine on Pain After Primary Total Hip Arthroplasty

St. Olavs Hospital

Status: Completed

Conditions: Osteoarthritis, Hip

Treatments: Procedure: local infiltration anesthesia using saline; Procedure: Multimodal analgesic regimen; Procedure: local infiltration anesthesia using Ropivacaine and Epinephrine

Study type: Interventional

Funder types: Other

Identifiers

NCT02359136

2012/1999

Details and patient eligibility

About

Background: The Local infiltration analgesic (LIA) technique has been widely used to reduce opioid requirements and improve the patient's mobilization after total hip arthroplasty (THA). However, the evidence for LIA in THA remains to be clarified.

Purpose: To evaluate whether a single shot LIA in addition to a multimodal analgesic regimen reduces acute postoperative pain and opioid requirements after THA.

Enrollment: 116 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• all patients receiving total hip arthroplasty in the study period

Exclusion criteria

• contraindications to receive spinal anesthetic, Dexamethasone or Acetaminophen.
• Patients who received general anaesthetic
• patients who will get a different operation than standard direct lateral surgery
• Patients with osteosynthesis to be removed in the same operation

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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116 participants in 2 patient groups, including a placebo group

LIA placebo

Placebo Comparator group

Description:

local infiltration anesthesia using saline i addition to multimodal analgesic regimen

Treatment:

Procedure: local infiltration anesthesia using saline

Procedure: Multimodal analgesic regimen

LIA Ropivacaine

Experimental group

Description:

local infiltration anesthesia using Ropivacaine and Epinephrine i addition to multimodal analgesic regimen

Treatment:

Procedure: Multimodal analgesic regimen

Procedure: local infiltration anesthesia using Ropivacaine and Epinephrine