Effect of Local Infiltration Anesthesia With Ropivacaine on Postoperative Pain After Hip Hemiarthroplasty

St. Olavs Hospital

Status: Completed

Conditions: Femoral Neck Fractures

Treatments: Drug: Saline; Drug: Epinephrine; Drug: Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02585011

2015/1201

Details and patient eligibility

About

At St.Olavs Hospital each year about 400 patients are treated for femoral neck fractures, 250 of them receiving hemiarthroplasty. Implementation of fast-track clinical pathways reduces morbidity and enhances recovery of patients undergoing hemiarthroplasty. One of the key prerequisites for early rehabilitation is optimized pain relief. Local infiltration anesthesia with Ropivacaine is part of a multimodal pain regimen for patients receiving hemiarthroplasty at St.Olavs Hospital, although the pain reducing effect of local Ropivacaine after hemiarthroplasty has not been investigated in clinical trials. In this study it will be investigated whether a single shot with Ropivacaine reduces acute postoperative pain and opioid requirement after hemiarthroplasty. The findings of this study will have a direct impact on patient treatment.

Enrollment: 123 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• scheduled for hemiarthroplasty at St. Olavs Hospital
• competent and willing to give consent
• able to be mobilized in the PACU and in the trauma ward unit.

Exclusion criteria

• contraindications for spinal anesthesia, Dexamethasone, Dolcontin or Acetaminophene
• receiving general anesthesia
• patients operated on with an approach different to standard direct lateral surgery
• receiving osteosyntheses
• receiving femoral block less than 4 hours before surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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123 participants in 2 patient groups, including a placebo group

Ropivacaine

Experimental group

Description:

Local infiltration anesthesia, single shot during surgery. 150 ml Ropivacaine (2mg/ml), added 0.5 ml Epinephrine (1mg/ml)

Treatment:

Drug: Ropivacaine

Drug: Epinephrine

Placebo

Placebo Comparator group

Description:

Single shot during surgery.150 ml saline

Treatment:

Drug: Saline