Effect of Location of Tetanic Stimuli on Photoplethysmogram

University of California San Francisco (UCSF)

Status: Completed

Conditions: Stress Reaction

Treatments: Device: Tetanic Stimulus

Study type: Interventional

Funder types: Other

Identifiers

NCT03648853

PT1801

Details and patient eligibility

About

The effect of the location of tetanic stimulus on photoplethysmography signals will be studies in patients under general anesthesia.

Full description

A 5 second 100 Hz 70 mA tetanic stimulus will be applied to three different locations in a random order in patients who are under general anesthesia. Tetanic stimuli are used routinely during general anesthesia to assess effectiveness of neuromuscular blockade. These tetanic stimuli are noxious stimuli that elicit a stress response which can be quantified using photoplethysmography. This study investigates if the magnitude of the tetanus induced stress response is dependent on the location of the tetanic stimulus as measured by photoplythysmography.

Enrollment: 12 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Surgical patients general anesthesia able to consent in english

Exclusion criteria

• regional anesthesia unable to consent in english under 18 yrs of age

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

intervention

Experimental group

Description:

all participants receive the same intervention

Treatment:

Device: Tetanic Stimulus