Effect of Low-calorie Diet on Serum Lipids, Adipokines, Insulin Resistance and Also Body Composition in Women With Metabolic Syndrome

Universidade Federal do Rio de Janeiro

Status: Completed

Conditions: Weight Loss; Insulin Resistance; Adipokines

Treatments: Other: Low-calorie diet

Study type: Interventional

Funder types: Other

Identifiers

NCT02087709

0535.0.000.325-08

U1111-1154-4418 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to evaluate the effect of a hypocaloric diet on biomarkers associated with insulin resistance, metabolic profile and body composition in women with Metabolic Syndrome.

Enrollment: 30 patients

Sex: Female

Ages: 30 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI of 30-34.9 kg/m2, diagnostic of metabolic syndrome based on National Cholesterol Education Panel ATPIII (2002)

Exclusion criteria

• Diabetes mellitus, non-treated thyroid disease, treatment with lipid-lowering drugs and glucocorticoids or weight loss treatment within the previous 3 months.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

30 participants in 1 patient group

Low-calorie diet

Experimental group

Description:

The subjects were prescribed a daily energy intake 500 kcal lower than the estimated energy requirement.

Treatment:

Other: Low-calorie diet