Effect of Magnesium Sulphate on Analgesia Following Knee Arthroplasty

Ufuk University

Status and phase: Unknown; Phase 4

Conditions: Postoperative Pain; Knee Arthroplasty, Total

Treatments: Procedure: continuous femoral nerve block; Drug: Magnesium Sulfate

Study type: Interventional

Funder types: Other

Identifiers

NCT03695640

MgTKA

Details and patient eligibility

About

This study is designed to investigate the effect of magnesium sulfate added to levobupivacaine in continuous femoral nerve block following total knee arthroplasty.

Full description

Pain after knee arthroplasty is a serious concern. This study was designed to investigate the effect of magnesium sulfate added to levobupivacaine in continuous femoral nerve block on analgesic requirements following total knee arthroplasty.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• scheduled for elective unilateral primary total knee arthroplasty

Exclusion criteria

• Patient refusal to enroll in the study
• Patient refusal of neuraxial anesthesia
• Existence of contraindications for neuraxial anesthesia
• Known history of allergy to any of the study drugs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Group L

Active Comparator group

Description:

continuous femoral nerve block with levobupivacaine

Treatment:

Procedure: continuous femoral nerve block

Group LM

Experimental group

Description:

continuous femoral nerve block with levobupivacaine and magnesium sulfate

Treatment:

Drug: Magnesium Sulfate

Procedure: continuous femoral nerve block