Effect of Manual Therapy on Migraine in Postmenopausal Women

Cairo University (CU)

Status: Not yet enrolling

Conditions: Migraine

Treatments: Drug: Non-steroidal anti-inflammatory drugs (NSAIDs); Other: Manual therapy techniques

Study type: Interventional

Funder types: Other

Identifiers

NCT07127107

P.T.REC/012/005876

Details and patient eligibility

About

The purpose of the study is to determine the effect of manual therapy on migraine in postmenopausal women.

Full description

Menopause is a period of great changes to women's bodies and minds. Alterations to body image and emotions, psychological adjustment to a new phase of life and worries about the higher prevalence of severe diseases and cognitive dysfunction all contribute towards negatively affecting the quality of life of menopausal patients. Symptoms that are typical of hormonal deprivation and aging are prevalent and distressful to many, often requiring individual counseling and specific therapies. Some of the symptoms are manageable and headache is certainly a modifiable parameter if given the appropriate treatment. About one third of the women had experienced worsening of their primary headaches after their last menstrual period, which contradicts the popular belief that "after menopause the headache gets better.

Migraine is a severe headache often felt as a throbbing pain - and usually occurring on one side of the head. It often comes with nausea or vomiting, and a heightened sensitivity to light or sound. The headache is such that it stops doing what is normally do and can last from four to 72 hours .

Soft tissue massage of the paraspinal muscles, jaw muscles will all help decrease the muscle spasm of tension headaches. Joint Manipulation: this can be done with manipulative techniques or gentle articulation techniques to encourage joint release and movement By manipulating the bones of skull and the dura mater that is a membrane just below the skull, craniosacral therapy also relieves arterial pressure to ease pain.

There is dearth of knowledge regarding the effect of manual therapy on migraine in postmenopausal women. This study, therefore, contributes valuable insights to a relatively unexplored area of

Enrollment: 40 estimated patients

Sex: Female

Ages: 50 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All women are postmenopausal at least one year following last menstruation.
• They are suffering from migraine.
• Their ages will range from 50 to 60 years old.
• Their body mass index (BMI) will not exceed 30 Kg/m2.
• Women with regular or irregular attacks of migraine.

Exclusion criteria

• Artificial or premature menopause
• Recent head trauma.
• Cerebral aneurysm or rupture.
• Tumors.
• Acute intracerebral bleeding.
• Hormonal replacement therapy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Non-steroidal anti-inflammatory drugs (NSAIDs) group

Active Comparator group

Description:

The participants will receive non-steroidal anti-inflammatory drugs (NSAIDs) to relieve the pain and symptoms of a migraine attack and help prevent further migraine attacks

Treatment:

Drug: Non-steroidal anti-inflammatory drugs (NSAIDs)

Manual therapy group and non-steroidal anti-inflammatory drugs (NSAIDs) group

Experimental group

Description:

The participants will receive the same medical treatment (non-steroidal anti-inflammatory drugs (NSAIDs)) plus manual therapy techniques for 3 times per week for 8 weeks.

Treatment:

Other: Manual therapy techniques

Drug: Non-steroidal anti-inflammatory drugs (NSAIDs)