Effect of Maternal Obesity on Labour Induction in Postdate Pregnancy

Kasr El Aini Hospital

Status: Completed

Conditions: Induced; Birth; Obesity

Treatments: Drug: Misoprostol

Study type: Observational

Funder types: Other

Identifiers

NCT02788305

9898 (Other Identifier)

Details and patient eligibility

About

This study investigate the progression of labour in 144 normal weight pregnant women (BMI <30) and 144 obese pregnant women (BMI >30) , not in labor admitted for induction of labor. These women are to be investigated for success of induction of labor.

Full description

• This prospective study will be conducted for 144 obese and 144 non obese ), post date (>41 wks), not in labor.

• Woman is classified as obese if BMI >=30.

• Prolonged pregnancy was defined as delivery on or after (41+0 weeks) of gestation.

• First informed consent will be obtained.

• Determination of gestational age

• Proper history taking, general and abdominal examinations will be done then digital examination will be performed to determine bishop score.

• And obstetric U/S scan will be done and by which the following data will be obtained :

  • Fetal biometry
  • Fetal heart activity
  • Presentation
  • Localization of the placenta.
  • Amount of amniotic fluid.
  • Exclude multifetal pregnancy.

• Induction of labor will be done using vaginal misoprostol according to the estimated Bishop score.

Enrollment: 288 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pregnant woman.

  • Post date >= 41 weeks.
  • Absent onset of labor.
  • Patient acceptance to join the study after signing an informed consent.

Exclusion criteria

• Placenta previa and or vasa previa.
• Previous caesarean section(CS).
• Multiple gestation
• Any patient who will refuse to be a part of the study.
• Intra- uterine fetal death (IUFD).

Trial design

288 participants in 2 patient groups

non obese

Description:

BMI\<30. Misoprostol is given for induction of labour according to Bishop score

Treatment:

Drug: Misoprostol

obese

Description:

BMI\>30. Misoprostol is given for induction of labour according to Bishop score

Treatment:

Drug: Misoprostol