Effect of Mediterranean and Hypolipemic Reduction Diet in Obese Patients

University of Zagreb

Status: Completed

Conditions: Obesity

Treatments: Behavioral: Weight reduction program

Study type: Interventional

Funder types: Other

Identifiers

NCT02259244

006-0000000-3521

Details and patient eligibility

About

The purpose of this study is to evaluate the combined effect of physical activity and adherence to Mediterranean diet or Hypolipemic Reduction diet on parameters of oxidative stress in obese patients enrolled in the weight management reduction program.

Enrollment: 124 patients

Sex: All

Ages: 18 to 69 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI ≥ 30 kg/m2

Exclusion criteria

• newly diagnosed diabetes, hypertension or cardiovascular disease
• change in antihypertensive therapy and antidiabetic therapy in the period of 3 months prior to the commencement of the study
• insulin therapy
• alcohol consumption >500 g of alcohol/week in the last year
• pregnancy or breast feeding
• use of drugs affecting weight control (eg. weight loss medication or systemic glucocorticoids)

Trial design

124 participants in 2 patient groups

Mediterranean diet+physical activity

Experimental group

Description:

Mediterranean diet based on 1573 kcal/day with the goal of consumption of 30 ml/day of olive oil, 56g/week of nuts, 3-4 servings/week of fish, 3 servings/day of fruits, 2-3 servings/day of vegetables, 3 servings/week legumes and white meat instead of red meat

Treatment:

Behavioral: Weight reduction program

Hypolipemic reduction diet+physical activity

Active Comparator group

Description:

Hypolipemic reduction diet based on 1287 kcal/day with the goal of consumption of 3 servings/day of fruits, 2-3 servings/day of vegetables, 3 servings/week legumes and white meat instead of red meat, non-fat or low-fat dairy products

Treatment:

Behavioral: Weight reduction program