Status and phase
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About
This study was aimed to investigate the effect of metformin on the gut microbiota and glycemic control in newly diagnosed type 2 diabetes patients.
Full description
This study was aimed to investigate the effect of metformin on the gut microbiota and glycemic control in newly diagnosed type 2 diabetes patients. All the recurited patients were treated with metformin 1500-2000mg daily for 3 months. Stool specimens and blood samples were collected at the beginning and 3 months later.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
newly diagnosis type 2 diabetes ,HbA1c >7 %
Exclusion criteria
history of cardiovascular disease, hypertension, severe renal dysfunction defined as glomerular filtration rate < 45 mL/min/1.73 m2; severe illness or diabetic ketoacidosis within 30 days, inability to tolerate ≥500 mg metformin twice per day and pregnancy.
Primary purpose
Allocation
Interventional model
Masking
52 participants in 1 patient group
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Data sourced from clinicaltrials.gov
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