Effect of Mindfulness Training on Sleep and Inflammation Among Older Adults With Sleep Problems (MAPS)

University of California, Los Angeles (UCLA)

Status and phase: Completed; Phase 2; Phase 1

Conditions: Inflammation; Sleep Problems

Treatments: Behavioral: Sleep Education; Behavioral: Mindfulness Meditation

Study type: Interventional

Funder types: Other

Identifiers

NCT01534338

MH019925

Details and patient eligibility

About

The primary aim of the study is to test the effect of mindfulness training on sleep parameters among older adults with insomnia symptoms

The secondary aims are to examine if changes in mindfulness meditation practice (daily log) and level of mindfulness (self-report) are associated with changes in sleep parameters, and to determine if mindfulness training is associated with in vitro biological markers of peripheral inflammation

Enrollment: 48 patients

Sex: All

Ages: 55+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men and women (all races and ethnicities) 55 years of age and older
• Have current problems sleeping
• Fluent in English
• Able to understand and provide signed informed consent
• Willing to be randomly assigned to treatment condition

Exclusion criteria

• Individuals currently undergoing major medical treatment such as surgery, radiation, or immunotherapy
• Individuals living outside of a 20 mile radius from the UCLA Medical Center
• Individuals with current substance dependence

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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48 participants in 2 patient groups

Mindfulness Meditation

Experimental group

Description:

The MAPs program is based on experiential training in mindfulness meditation offered at the UCLA Mindful Awareness Research Center (MARC). A certified UCLA instructor will provide didactic training in mindfulness meditation in a group-based setting. Participants will be guided through in-class meditation practices and will be assigned daily meditation homework. Active program components include sitting and walking somatosensory-focused meditation, audio-guided body scan meditation, and loving kindness meditation. Participants will attend weekly 2-hour classes for a total of 6 weeks and participants will monitor their sleep with a daily sleep diary. In addition to the MAPs training, sleep hygiene material will also be presented to match the sleep hygiene material in the sleep education condition.

Treatment:

Behavioral: Mindfulness Meditation

Sleep Education

Active Comparator group

Description:

The sleep education condition is founded on knowledge acquisition. In the sleep seminar condition, a trained health educator will provide didactic presentations on sleep, sleep hygiene, sleep problems, and potential solutions to sleep problems in a group-based setting. Active components of sleep education include increasing knowledge of sleep biology, identifying characteristics of healthy and unhealthy sleep, sleep problems, and self-monitoring of sleep behavior. Participants attend weekly 2-hour classes for a total of 6 weeks and participants will monitor their sleep with a daily sleep diary. The health education condition is comparable to MAPs in terms of time, attention, group support, and participant expectancy of a benefit in sleep parameters.

Treatment:

Behavioral: Sleep Education