Effect of Moringa Oleifera Leaves on Glycemic Control of Women With Type 2 Diabetes

University of Milan

Status: Completed

Conditions: Type 2 Diabetes

Treatments: Dietary Supplement: Supplementation of Moringa oleifera leaf powder

Study type: Interventional

Funder types: Other

Identifiers

NCT06517602

10-11-2018

Details and patient eligibility

About

The objective of this clinical trial was to understand whether supplementation of Moringa oleifera leaf powder improved glycemic management in Sahrawi women with type 2 diabetes living in refugee camps. The main question sought to be answered was:

• Does daily supplementation of Moringa oleifera leaf powder, in addition to oral hypoglycemic therapy, improve glycosylated hemoglobin and fasting blood glucose?

Researchers compared Moringa supplementation with no Moringa consumption to see if Moringa oleifera worked to improve glycemic control.

Participants had to:

• Take Moringa oleifera leaves daily or abstain from consuming Moringa for 3 months.
• Consistently take prescribed oral hypoglycemic agents
• Undergo clinical examinations and measurement of biochemical, metabolic and body composition parameters at the time of recruitment and at the end of the study.

Enrollment: 52 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of type 2 diabetes for at least 1 year
• Absence of advanced retinopathy, terminal renal failure, active diabetic ulcers, amputations, and heart failure
• Treatment with only oral hypoglycemic drugs.

Exclusion criteria

• Diagnosis of type 1 diabetes
• Pregnancy or lactation
• Treatment with insulin.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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52 participants in 2 patient groups

Moringa

Experimental group

Description:

The experimental group received for 3 months a daily supplementation of 10g of Moringa oleifera leaf powder to consume within the two main meals.

Treatment:

Dietary Supplement: Supplementation of Moringa oleifera leaf powder

Control

No Intervention group

Description:

The control group were asked to refrain from consuming Moringa oleifera leaves throughout the study period (3 months).