Effect of Motor Cortex Versus Sacral Magnetic Stimulation in Multiple Sclerosis Patients With Urinary Tract Dysfunction

Cairo University (CU) logo

Cairo University (CU)

Status

Completed

Conditions

Lower Urinary Tract Symptoms
Multiple Sclerosis

Treatments

Other: magnetic stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT03434873
30091981

Details and patient eligibility

About

This work is intended to assess the effect of repetitive magnetic stimulation on the sacral roots versus repetitive magnetic stimulation on motor cortex in multiple sclerosis patients with the lower urinary tract dysfunction.

Full description

Twenty Multiple sclerosis patients with lower urinary tract symptoms will be receiving repetitive magnetic stimulation on sacral roots. Another twenty Multiple sclerosis patient with lower urinary tract symptoms will be receiving repetitive magnetic stimulation on motor cortex. Treatment outcome will be assessed and compared between the two groups. Twenty trains of 50 stimuli at 5 Hz (train duration: 10 seconds) separated by a 40-second pause were delivered for a total of 1000 pulses (total duration: 16 minutes) once a day for four consecutive days for two weeks.

Enrollment

40 patients

Sex

All

Ages

18 to 45 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Multiple Sclerosis patients (diagnosed by McDonald criteria 2010) with lower urinary tract dysfunction
  • Adults more than 18 years
  • Unresponsiveness to medical treatment
  • Urodynamic diagnosis of detrusor overactivity and/or detrusor underactivity and/or detrusor-sphincter dyssynergia

Exclusion criteria

  • Urinary tract infections
  • Pregnancy

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

40 participants in 2 patient groups

Sacral magnetic stimulation
Active Comparator group
Description:
Twenty trains of 50 stimuli at 5 Hz (train duration: 10 seconds) separated by a 40-second pause were delivered for a total of 1000 pulses, once a day for four consecutive days for two weeks, over sacral roots
Treatment:
Other: magnetic stimulation
Cortical magnetic stimulation
Active Comparator group
Description:
Twenty trains of 50 stimuli at 5 Hz (train duration: 10 seconds) separated by a 40-second pause were delivered for a total of 1000 pulses, once a day for four consecutive days for two weeks, over motor cortex
Treatment:
Other: magnetic stimulation

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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