Effects of Music Combined With CBT on Chronic Subjective Tinnitus

Sun Yat-sen University

Status: Completed

Conditions: Subjective Tinnitus; Sleep Disorder

Treatments: Behavioral: music-CBT

Study type: Observational

Funder types: Other

Identifiers

NCT06505473

SYSKY-2024-453-01

Details and patient eligibility

About

This study retrospectively analyzed the first and second visit data of chronic subjective tinnitus patients who received music combined with cognitive behavioral therapy in our hospital in recent years. Behavioral tests and tinnitus questionnaires, as well as sleep and depression scores, were used to analyze the therapeutic effects of this approach. EEG results were analyzed as a potential neurobiological marker to explore the neural mechanism of tinnitus symptom improvement.

Full description

The subjects of this study were chronic subjective tinnitus patients and normal controls who were treated with music therapy combined with cognitive behavioral therapy (music-CBT) in the Department of Otolaryngology of Sun Yat-sen Memorial Hospital from December 2016 to March 2024 and who had completed re-examination. The pre- and post-music-CBT data of past patients who met our study conditions were collected for retrospective statistics. The complete sample data included medical history, pure tone audiometry, tinnitus matching, tinnitus questionnaires (Tinnitus Handicap Inventory, Visual Analog Scales, tinnitus Functional Index), sleep quality questionnaire (Pittsburgh Sleep Quality Index), and depression questionnaire (Hamilton Depression Scale -24 items). The resting state electroencephalogram (rs-EEG). Retrospective statistical analysis was conducted to determine the clinical efficacy and influencing factors of music-CBT for chronic subjective tinnitus at 3 months and long term. Finally, the neural mechanism of music-CBT for tinnitus treatment was analyzed based on rs-EEG results.

Enrollment: 28 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• adults aged between 18 and 60
• a total score of 18 or higher on THI
• a constant tinnitus that can be matched
• right-handed
• no significant medical or psychiatric conditions

Exclusion criteria

• intermittent, pulsating or objective tinnitus
• central nervous system disease
• cognitive impairment
• other contraindications for EEG testing

Trial design

28 participants in 3 patient groups

pre-operative results

Description:

pre-operative period test results, baseline data.

Treatment:

Behavioral: music-CBT

post-operative results

Description:

post-operative period test results, review data.

healthy control

Description:

Subjects with no tinnitus and matched baseline information