Effect of Myoma Removal on Blood Pressure and Erythropoetin Level

Shiraz University of Medical Sciences

Status: Completed

Conditions: Hypertension; Myoma

Treatments: Procedure: myoma removal

Study type: Interventional

Funder types: Other

Identifiers

NCT00898170

88-2505

Details and patient eligibility

About

The effect of myoma removal was studied on 28 patients with hypertension and myoma by holter monitoring and erythropoetin level check.

Full description

Background:

Myoma is the most common gynecoid tumor and produces many vasoactive substances, which may be a cause for secondary hypertension. Early reports suggested the association of myoma and hypertension. We studied the effect of myoma removal on hypertension and erythropoietin level to evaluate this hypothesis.

Patients & Methods:

In this single centered prospective cohort study, in twenty eight patients who were candidates for myomectomy due to myoma, 24 hour holter monitoring of blood pressure and serum erythropoietin were checked before and 6 weeks after hysterectomy.

Enrollment: 28 patients

Sex: Female

Ages: 22 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• candidate for myoma removal by hysterectomy
• operable
• hysterectomy is indicated

Exclusion criteria

• patient refusal
• inoperable patients
• other secondary cases of hypertension

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: Quadruple Blind

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28 participants in 1 patient group

myoma, with or without hypertension

Experimental group

Description:

those with myoma with or without hypertension in holter monitoring

Treatment:

Procedure: myoma removal