Effect of Nano Care Gold on Marginal Integrity of Resin Composite

Cairo University (CU)

Status and phase: Completed; Phase 1

Conditions: Caries Class Ii

Treatments: Other: Nano Care Gold; Other: Chlorhexidine; Other: No intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT03669224

CEBD-CU-2018-09-04

Details and patient eligibility

About

The aim of this study to detect the effect of Nano Care Gold on marginal integrity of resin composite restoration

Full description

This study will be divided into 3 groups (control, Nano Care Gold, Chlorhexidine). Both materials will be used as a surface pre-treatment. Their effect on marginal integrity will be evaluated through evaluation of marginal adaptation, marginal staining, post-operative sensitivity. The follow up period is one year

Enrollment: 57 patients

Sex: All

Ages: 17 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• (1) Patients with at least two class II cavities (2) 17-50 years old (3) Males or females (4) Good or hygiene (5) Good general health (6) Cooperative patients (7) Subjects who signed the informed consent

Exclusion criteria

1. Patients younger than 17 years or older than 50 years old
2. Pregnant females
3. Disabilities
4. Systemic disease or severe medical complications
5. Heavy smoking
6. Lack of compliance

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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57 participants in 2 patient groups

Nano Care Gold

Experimental group

Description:

Silver and Gold nano particles suspended in 70 % isopropyl alcohol. It will be used for cavity pre-treatment. This arm will be compared with no intervention (negative control).

Treatment:

Other: No intervention

Other: Nano Care Gold

Chlorhexidine

Active Comparator group

Description:

2% chlorhexidine gluconate solution will be applied to prepared cavity followed by adhesive system then resin composite. This arm will be compared with no intervention (negative control).

Treatment:

Other: Chlorhexidine

Other: No intervention