Effect of Naringenin and Beta Carotene on Energy Expenditure

Pennington Biomedical Research Center

Status: Completed

Conditions: Safety Issues; Glucose Metabolism; Energy Expenditure

Treatments: Dietary Supplement: naringenin and beta carotene

Study type: Interventional

Funder types: Other

Identifiers

NCT04697355

IRB FWA 00006218

Details and patient eligibility

About

This study is designed to test the effects of the combination of naringenin (from an extract of sweet oranges) and beta carotene on energy expenditure and glucose metabolism in a single human subject.

Full description

The subject will be treated for 8 weeks with the combination of naringenin + beta carotene.

We will conduct the following assessments before the treatment and at the end of eight weeks.

1. Resting metabolic rate
2. Oral glucose tolerance test with glucose and insulin
3. Ambulatory blood pressure
4. Recording of adverse events
5. Body weight

Enrollment: 1 patient

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Fasting blood glucose < 200mg/dL

Exclusion criteria

• Known allergy to citrus fruits

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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1 participants in 1 patient group

Naringenin + Beta carotene

Experimental group

Description:

Subject will ingest 300 mg naringenin three times/day and 6 mg beta carotene two times/day

Treatment:

Dietary Supplement: naringenin and beta carotene