Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome

U

University of Oklahoma (OU)

Status

Completed

Conditions

Chronic Obstructive Pulmonary Disease
Obstructive Sleep Apnea

Treatments

Diagnostic Test: CPET

Study type

Observational

Funder types

Other

Identifiers

NCT01033266
14587/2895

Details and patient eligibility

About

Nasal CPAP will improve cardiopulmonary exercise test (CPET) performance in patients with overlap syndrome(COPD and OSA). Nasal CPAP is proven to improve cardiopulmonary exercise testing in patients with OSA. The investigators hypothesis is that patients with overlap syndrome will have a greater improvement in their cardiopulmonary exercise testing besides a possible improvement in their lung function test and airway resistance.

Full description

Patients presenting to the Oklahoma City VA sleep clinic with obstructive sleep apnea syndrome and a desire to initiate CPAP treatment will be included if they have overlap syndrome. Patients will undergo a spirometry and CPET before being started on CPAP as part of standard clinical care. The CPET will be repeated after 8-12 weeks of CPAP use. Patients will be excluded if they have any contraindication to mild exercise or they cannot perform an exercise test due to limited mobility.

Enrollment

12 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Obstructive sleep apnea (OSA)
  • COPD

Exclusion criteria

  • Inability to perform exercise test due to musculoskeletal limitation
  • Cardiac condition preventing patient from mild exercise
  • Continuous oxygen supplement

Trial design

12 participants in 1 patient group

CPET CPAP
Treatment:
Diagnostic Test: CPET

Trial contacts and locations

2

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems